Criminal Psychology

Lin Chen and Mr. Xiao Zhan found a seat and sat down.

The promotional video of Zhourui Pharmaceuticals was repeatedly played on the large screen in the venue, and the booming sound spread all around through the speakers.

The aerial camera swept across the Zhourui pharmaceutical building and landed on the corporate logo in the shape of a blue dove of peace.

"We are Zhourui Pharmaceuticals, committed to curing life and improving the quality of life for all mankind..."

The narration of a righteous male voice sounded, and the sliding door of Zhou Rui Pharmaceutical Hall opened. Following the camera, you can see the energetic employees in the pharmaceutical company.The camera keeps going upwards and passes through the R&D laboratory. On both sides of the workbench are employees in light blue dustproof suits. The picture appears orderly, bright and clean.

This reminded Lin Chen of the dirty mining area deep in the rainforest, and everything was in stark contrast.

The male voice in the promotional video continued to read aloud: "Zhou Rui Pharmaceutical has the world's most advanced R&D team with world-class R&D capabilities. We are determined to forge ahead and invest more than 6 billion yuan in research and development of new drugs every year. As of June this year, A total of 52 new drugs have been launched on the market..."

Many charts appeared on the screen, showing Zhou Rui Pharmaceutical's R&D investment and related R&D results.

In short, the press conference is of course also a corporate promotional meeting, and these things must be necessary.Lin Chen took a brief look and felt that Zhou Rui Pharmaceutical had made some contributions over the years.

After playing the deafening and passionate corporate promotional video dozens of times, it finally stopped.

Lin Chen noticed that there were some gray-haired people in the front row, accompanied by the staff of Zhou Rui Pharmaceutical, and some young and middle-aged people, who should be the backbone of hospitals or research institutes.

Lin Chen was suddenly squeezed by Mr. Xiao Zhan. He looked aside, and Mr. Xiao Zhan, the second generation of the chemical plant, said excitedly: "My God, Mr. Lin, did you see it, my God, my God, Academician Zhang Come too!"

Lin Chen didn't know, so when he looked in the front row, he couldn't see anything from those backs. But just now, among the experts in the front row, he seemed to see the doctor who asked them to come to the promotion meeting yesterday.

Like the excited Mr. Zhan, there was a commotion at the scene.

Without asking any questions, Mr. Xiao Zhan took the initiative to explain in his ear: "That's Academician Zhang from the Institute of Pharmaceutical Sciences, Chinese Academy of Sciences! The best of the best!"

"you recognize?"

"No... I don't know..." Mr. Xiao Zhan was suddenly embarrassed, and immediately languished, "I... I wanted to study for a doctorate under Academician Zhang, but I didn't... passed the exam."

The top expert from the Institute of Pharmaceutical Research was invited to stand for a pharmaceutical company on the spot, which somewhat subverted his cognition.

"Is this appropriate?" Lin Chen asked, "Academicians are willing to come to business?"

Mr. Xiao Zhan hurriedly pushed him, and said seriously: "This is not a trick, Mr. Lin, please keep your voice down."

People around cast a lot of gazes, so Lin Chen shut up. In this kind of place, it is obvious that too many words will be lost.

"I don't know."

"You may not understand these problems in the pharmaceutical industry." Mr. Xiao Zhan lowered his voice, "Look, if a new drug is to be promoted and marketed to cure patients, who will use it for whom?"

"Of course it's from the doctor to the patient."

"Mr. Lin, you are right... But, there are many types of drugs on the market, even simple antipyretics, there are a wide variety of them, so how do doctors obtain new drug information to make a distinction and choose a certain drug?" For a certain patient?"

"Doctors always have their own way of knowing..."

"Of course, but once doctors are really busy with their work, there are too many types of drugs, so one of the main ways for doctors to understand drugs is through the promotion of drug manufacturers themselves. Generally, when a new drug is launched, the first thing drug manufacturers do It is a large-scale promotional activity, telling the treatment mechanism, curative effect, and clinical trial results of this drug... The arrival of experts is of course the result of the invitation of the pharmaceutical company, but this is also the best opportunity for doctors to learn about new drugs. In fact, in the medical system The thinking is also very stubborn. The promotion of a new treatment idea and drug sometimes takes a long time before this drug can completely replace the previous class of drugs and be accepted by people. Only if the replacement is successful can mutual benefit be truly achieved. The process of reciprocity and ultimately benefiting patients." Mr. Xiao Zhan said.

Lin Chen sighed softly: "There is no big problem with what you said. After all, in essence, there is no commercial benefit from the use of drugs on patients, and there is no fund to promote a new round of research and development..."

"Mr. Lin, it's really amazing that you can think this way. At least it's different from those who think that doctors and drug companies are in collusion and insist on making hard-earned money from patients. In fact, if a pharmaceutical company treats a certain disease If they can’t make money, then they probably won’t invest a lot of money in research and development of new products. For example, vaccines for niche viruses are rarely made, and for brain injury rehabilitation drugs like Nordren, Guangzhourui Pharmaceuticals itself It has been produced and updated for many generations..."

Mr. Zhan was about to start chattering again.

"Mr. Xiao Zhan." Lin Chen interrupted him.

"what did you say?"

"I said, when you talk about your expertise, you suddenly become less nervous."

"I...I'm not...not nervous..."

Mr. Xiao Zhan blushed, and at the same time, the lights in the venue were dimmed, and someone walked onto the stage slowly.It was a middle-aged man with a big belly. The middle-aged man wore a pair of gold-rimmed glasses and was half bald. He was the chairman of Zhou Rui Pharmaceutical.

"Experts from all walks of life and friends from all walks of life are welcome to attend the promotion conference of Nordlen, a new drug of Zhourui Pharmaceutical. A lot of things have indeed happened about the launch of Nordlen. Recently, Zhourui Pharmaceutical has also conservatively questioned whether the drug Nordlen It is indeed fateful, including ourselves, who once thought that this drug may no longer be able to contribute to the cure of the disease. But after all, it is an epoch-making new drug. We firmly believe in its curative effect, and it should serve all patients. Therefore, we recently A lot of efforts have been made to make it finally listed. Here, I also thank friends from all walks of life for their help."

There was thunderous applause from the audience, and the chairman of Surrounding Pharmaceuticals did not shy away from the recent problems surrounding Nordren, but used a very understatement to mention one of them.

Lin Chen looked at everything on the stage calmly.

Mr. Chairman waved his hand: "Okay, I won't talk nonsense, please watch Nordren's promotional video."

The big screen suddenly brightened, and a new drug configuration appeared, and the model on the screen rotated 360 degrees.

Many people were flipping through the promotional materials that were placed on each seat at that time, Mr. Xiao Zhan read it very seriously, and Lin Chen began to pay attention to the reactions of different people on and off the stage.

"The reason why Nordren is a brand-new brain science drug is that it abandons the usual treatment ideas of dredging and trapping leaks in the past, and pays more attention to neuron repair. Its active ingredient is TON, which was developed decades ago. , obtained from a bacterial culture found in the Dana rainforest soil by our company. The researchers designed and synthesized various derivatives, hoping to enhance the fat solubility of the drug to cross the blood-brain barrier. Once it enters the brain , the derivative drug designed by Nordren will undergo rapid metabolic changes and become a new active ingredient. The information in your hand contains relevant clinical experimental evidence, according to the relevant results..."

"Did you find anything?" Lin Chen turned his head and asked.

Mr. Xiao Zhan was stunned: "What discovery?"

Only then did Lin Chen realize that the other party was not Xing Conglian who came to investigate the case with him, but just an ordinary chemical expert who wanted to restore the reputation of his father's company.

"Is Nordren really as miraculous as it says?"

"Ah? Miraculous?" Mr. Xiao Zhan put it down, "It's quite powerful, and the idea is very new, but... maybe it can't be called miraculous."

Lin Chen frowned: "Didn't you mean a new way of thinking?"

"The most novel feature of Nordren's drug is the disassembly and reorganization of the active ingredients to pass through the blood-brain barrier. The biggest function of the blood-brain barrier is to prevent compounds in the blood from entering the brain. The advantage is to prevent harmful substances from invading the brain, but Similarly, the blood-brain barrier also blocks the entry of therapeutic drugs, thereby affecting the therapeutic effect." The presentation on the stage continued, while Mr. Xiao Zhan explained to him in more plain language.

"and then?"

"Then, Nordlen is actually a double-drug fixed-dose compound of Zhourui Pharmaceutical's previous generation cardiovascular and cerebrovascular drug TERN and the anti-platelet agent ADP. TERN has changed its configuration and introduced the TON component just mentioned. The idea of ​​​​the new drug released is very powerful, and it is indeed something I have never seen before."

Mr. Xiao Zhan's tone was normal and relaxed, but Lin Chen was terrified.

He rubbed the space between his brows. He always felt that Mr. Zhan's words contained extremely important and critical information, but this information had been hidden in the most obvious place because of their lack of professional medical knowledge.

He clenched his fist and finally made up his mind.

"Come out with me." He patted Xiao Zhan on the shoulder.

"Ah, what, the meeting isn't over yet." Mr. Xiao Zhan didn't know why.

"Come out with me." Lin Chen emphasized.

The corridors of the hotel outside the venue carried the unique fragrance of hotel incense. When they came out, they were routinely checked by the guards as usual.

Lin Chen led Mr. Zhan to walk casually in the corridor, and finally Kaiku said, "I have a question, and I would like you to analyze it for me."

"You...why are you so polite."

"Just now on the stage, Chairman Zhou Rui talked about the ups and downs of his company Nordrum before going public. What do you think of it?"

"I...I don't know..."

"I mean, do you think there's something wrong with Nordren?"

"Have you always thought there was something wrong with Nordren?"

Lin Chen saw Mr. Xiao Zhan's expression, and felt that the young man probably remembered his rebuttal to the attending doctor at the entrance of the MRI room yesterday.

"There shouldn't be any problem if it can pass the test of the Food and Drug Administration, and after so many clinical trials, unless Zhou Rui Pharmaceutical deliberately falsifies the data, otherwise the curative effect is indeed there."

"What about the side effects? Will Nordren have any strong side effects?"

"It's hard to say about side effects. For example, Herceptin, a breast cancer drug, was found to have symptoms and signs of cardiac dysfunction during the later stage of treatment. We all say that the drug is three-point Poison, you said that a certain drug must have no side effects, it is not very likely..."

Lin Chen quietly listened to Xiao Zhan Xiaosheng's narration, and did not interrupt the young man.

"The side effects are within the controllable range, that is to say, within a certain data range, it is acceptable, and Zhou Rui Pharmaceutical is not stupid. If they know that Nordrum has strong side effects, why should they promote it? Suffering claims have to make them lose their underwear."

Lin Chen fell into deep thought.

They have repeatedly mentioned the problem that Xiao Zhan mentioned. Now it seems that, based on all the information in the past few days, some things can be found.

First, there shouldn't be much problem with the drug Nordren itself, otherwise Zhourui Pharmaceuticals wouldn't promote this drug on a large scale.

Second, there were unspeakable problems within Zhourui Pharmaceuticals, so that they replaced all suppliers.

Third, as the R&D director of Nordren, Stankang should have discovered some things, and she was killed by Chen Lian before she wanted to reveal these things.

Fourth, for a long time, Shen Lian used Duanyang to prevent Nordrum from going public by fabricating lies.

But the question is, what kind of conclusions can be drawn from this information?

Lin Chen looked at the young man beside him, and asked, "If someone goes to great lengths to prevent Nordrum from going public, what do you think is the motive of that person?"

"Are you talking... are you talking about Zhou Rui Pharmaceutical's competitors?" Mr. Xiao Zhan asked nervously.

"Competitors?"

"Because Nordren's idea is really new. If it can be successfully promoted on a large scale, there is no room for survival for drugs that will run out of other manufacturers' old ideas. Except for competitors, I... I can't think of anyone who would not miss Nordren. What about going public?"

"But what if it's Zhou Rui's internal staff who don't want a certain drug to be made?"

"It may also be a competition among internal teams. For example, if the company pushes your drug, then the previous generation of drugs I developed will be forced to withdraw from the market slowly, or the project of the new generation of drugs I am developing will be cancelled... "

"Previous drug?"

Lin Chen suddenly felt extremely horrified: "You just said, what is the relationship between Nordren and Zhou Rui Pharmaceutical's previous generation of cardiovascular and cerebrovascular drugs?"

"Nordlun is a new type of drug produced by remodeling the previous drug TERN and adding the new ingredient TON." Mr. Xiao Zhan wondered, "What's wrong?"

"Nordren is an improvement on the previous generation of drugs?"

"It's more complicated than improvement, this is not a simple inheritance relationship..."