Traveling through time and space.

Chapter 244 Brain Science Research and Application Exploration by Biotechnology Companies

Mu Yang took a break from the hectic grind of music copyright management at his cultural company. While still brimming with the sense of accomplishment from the orderly progress of his music copyright business, he set his sights firmly on the boundless possibilities of brain science research within the biotech sector. At a critical juncture as his biotech company fully embraced cutting-edge scientific research, brain science research and applied exploration seemed like a treasure trove shimmering with mysterious light, beckoning him to lead his team to greater heights. With a sense of mission and a deep concern for his biotech company's brain science research and applied exploration, Mu Yang hurried to the biotech company, determined to forge a new chapter in this challenging and promising field.

Brain Science Laboratory: A Frontier for Exploring the Mysteries of the Brain

Stepping into the biotechnology company's brain science laboratory, Mu Yang felt like stepping into a microcosm of science. A large MRI machine stood silently, emitting a soft, dim glow. Its delicate circuits, like mysterious threads, seemed to weave a secret code to the brain's unknown realms. A nearby electrophysiological recorder emitted a gentle hum, as if conducting a multidimensional dialogue with neurons deep within the brain. Researchers, neatly dressed in white coats, moved intently between various instruments, their eyes revealing a dedication and focus on scientific exploration.

"Hello everyone! Brain science research is the top priority of our company at this stage. It carries the hope for countless patients with brain diseases to regain their health. We must go all out and bravely climb to the top of science." Mu Yang's voice was firm and powerful, echoing in the laboratory like a huge bell, instantly igniting the enthusiasm of the researchers.

Dr. Lin, the head of the research team, walked forward quickly, holding a thick stack of experimental reports in his hand, his face filled with excitement and pride: "Mr. Mu, we have made significant progress in brain science research. By using neuroimaging and molecular biology techniques, we have a deeper understanding of the pathogenesis of Alzheimer's disease. We have discovered the abnormal expression of a specific gene, which is very likely to be one of the key factors leading to Alzheimer's disease." As Dr. Lin spoke, he handed the report to Mu Yang, his eyes flashing.

Mu Yang carefully flipped through the report, his expression focused. However, Dr. Lin's expression gradually grew serious. "However, Mr. Mu, brain science research requires a huge investment. The company has already invested [X] million yuan in advanced neuroimaging equipment, and the monthly cost of experimental reagents and consumables is as high as [X] million yuan. In addition, we also need a large amount of funds to recruit top scientific research talent and conduct large-scale clinical trials. The contradiction between this and the company's short-term economic benefits is becoming increasingly prominent, and the finance department is concerned about this. After all, it is difficult to see a significant return on investment in the short term, and the financial pressure is indeed considerable."

Mu Yang frowned slightly, and after a moment of contemplation, he said, "Dr. Lin, I understand the finance department's concerns, but we must view brain science research from a long-term strategic perspective. Once we achieve a major breakthrough, it will not only bring huge economic benefits to the company, but also bring good news to patients with brain diseases around the world, which will greatly enhance the company's social reputation and influence. We must communicate well with the finance department and let them understand that this is a strategic investment with far-reaching significance. In terms of fund use, we must be prudent, optimize experimental plans, and improve fund efficiency. At the same time, we must actively apply for various scientific research project funds to demonstrate our research strength and application prospects to the government and research institutions, and strive for more external financial support."

As research progressed, competition and conflict over the allocation of research resources among researchers gradually surfaced. At a meeting to coordinate experimental resources, Dr. Zhang, who oversees Parkinson's disease research, sounded particularly anxious: "We are conducting a key study on the pathogenesis of Parkinson's disease and urgently need a high-precision single-cell sequencer to analyze gene expression in neuronal cells. However, this equipment is currently occupied by the Alzheimer's disease research team, and our research progress has seriously lagged behind. According to the experimental plan, we must complete the analysis of cellular gene expression within this week, otherwise all our previous efforts will be wasted. We have already invested a lot of time and energy in this project, and the early experimental results urgently need to be further verified using this equipment."

Dr. Lin, who oversees Alzheimer's disease research, expressed embarrassment. "Our project is also at a critical stage. We're using this equipment to conduct functional validation experiments on key genes, and we simply can't give it up. Every project is crucial, and we're all facing tremendous research pressure. I hope we can understand each other."

The atmosphere instantly became tense, and Mu Yang quickly stood up to mediate: "Everyone, calm down first. Brain science research requires our various projects to work together and advance together. We will establish an experimental resource sharing mechanism to reasonably arrange equipment usage time according to the importance and urgency of the project. Develop a detailed equipment usage plan, such as allocating fixed usage time periods for each project team each week to ensure that each project can proceed smoothly. At the same time, we encourage everyone to strengthen collaborative research, share research results, and improve resource utilization efficiency. We can organize regular project exchange meetings for everyone to share research progress and problems encountered, and jointly explore solutions."

Neurology Department in Medical Institutions: Deep Integration of Scientific Research and Clinical Practice

To effectively apply the results of brain science research to clinical practice, Mu Yang visited the neurology department of a medical institution. The corridors were filled with the smell of disinfectant, and the eyes of the patients in the wards were filled with a longing for health. Dr. Li from the neurology department greeted Mu Yang warmly, his eyes revealing recognition and anticipation for collaborative research: "Mr. Mu, we are very excited about your company's brain science research results. These results are expected to bring revolutionary changes to the diagnosis and treatment of neurological diseases."

However, as the details of the collaboration were explored, problems gradually emerged. Dr. Li expressed some concern, "During the collaborative application process, the ownership of intellectual property and the distribution of benefits cannot be ignored. Our medical institution has invested significant clinical resources and expertise, and we hope to clarify the ownership of intellectual property and the proportion of benefits shared between both parties when the research results are translated into economic benefits. Furthermore, individual patient differences in clinical practice are significant, and precisely applying laboratory research results to each patient presents a major challenge."

Mu Yang listened carefully, thought for a moment, and then said, "Doctor Li, your concerns are very reasonable. Before cooperating, we will sign a detailed cooperation agreement to clarify the ownership of intellectual property rights and the method of profit distribution. Based on the investment and contribution of both parties in the cooperation, we will reasonably determine the profit distribution ratio. For example, in terms of intellectual property rights, we will clarify which achievements belong to both parties and which belong to each party; in terms of profit distribution, we will divide them according to a certain ratio based on the sales or profits of the products. To address the individual differences among patients, we can establish a large patient database, collect detailed clinical data, and use big data analysis and artificial intelligence technology to develop personalized diagnosis and treatment plans for each patient."

During the collaboration, the differences and conflicts between the culture of basic research, which focuses on theoretical exploration, and the culture of clinical application, which emphasizes practical application, gradually emerged. Dr. Lin said helplessly, "In our research, we focus more on theoretical breakthroughs and mechanism exploration, which requires a lot of time for basic experiments. However, clinical application focuses more on practical effects and the immediate needs of patients, hoping to quickly translate research results into practical treatments. This creates a certain contradiction. Although our research has achieved some theoretical results, it is still some distance away from practical application."

Dr. Li nodded in understanding, but he also had his own concerns: "We understand the rigor and complexity of scientific research, but clinical work is directly related to the lives and health of patients and must focus on practical results. We hope to accelerate the translation of research results while ensuring safety and effectiveness. After all, patients urgently need new treatments to improve their conditions. Moreover, the fast pace of clinical work, requiring rapid response to various emergencies, is difficult to reconcile with the rigorous and slow pace of scientific research."

Mu Yang patiently coordinated, "Everyone's starting point is for the benefit of patients. During the research process, researchers must fully consider the needs of clinical applications, optimize experimental plans, and try to shorten the cycle from research to application. Clinicians must also give researchers a certain amount of time and space to support them in conducting in-depth research. We can establish a joint R&D team with the participation of both parties to promote the close integration of scientific research and clinical practice. Let researchers go deep into the clinical frontline to understand the actual situation and needs of patients; at the same time, let clinicians participate in research projects and provide clinical experience and professional advice. In order to address the issue of work rhythm, a unified communication process and time nodes should be established to ensure efficient collaboration between the two parties."

Rehabilitation institution: Brain science helps patients regain their life

To explore the application of brain science in rehabilitation therapy, Mu Yang came to a rehabilitation institution. In the rehabilitation training room here, patients are diligently carrying out various rehabilitation training under the patient guidance of the staff. Every drop of sweat carries their desire to return to normal life. Director Zhao of the rehabilitation institution enthusiastically introduced the situation to Mu Yang. His rigor and responsibility for rehabilitation work were evident in his words: "Mr. Mu, we are very much looking forward to applying brain science to rehabilitation therapy. If we can design a personalized rehabilitation training program based on the principle of brain plasticity, it will greatly improve the patient's recovery effect."

However, Director Zhao also expressed his concerns: "Different medical and rehabilitation institutions have different cultures for scientific research and clinical practice, and their acceptance of applied brain science research also varies. Some institutions prefer traditional rehabilitation methods and are slow to accept new brain science concepts. While some institutions are willing to try new technologies, they generally have limited funds and face difficulties in purchasing advanced rehabilitation equipment. This, to a certain extent, restricts the application of brain science technology."

After some thought, Mu Yang said, "Director Zhao, we can take the following measures to address these issues. We should strengthen the promotion and training of new technologies, organize rehabilitation workers to participate in professional training courses and academic exchange activities, and let them gain a deeper understanding of the advantages and application prospects of brain science. We should also develop personalized promotion plans based on the characteristics of different institutions. For institutions with strong traditional concepts, we should first conduct small-scale pilot applications and let actual results speak for themselves. For institutions willing to try new technologies, we should increase support and provide more technical guidance and resources. Regarding funding, we can jointly apply for the government's special rehabilitation fund, or seek sponsorship from companies to introduce advanced rehabilitation equipment. At the same time, we should establish demonstration projects so that everyone can see the significant effects brought about by new technologies with their own eyes and increase their acceptance of new technologies."

Through a series of efforts, biotech companies have achieved remarkable initial results in brain science research and application. In laboratories, a deeper understanding of the pathogenesis of brain diseases has been achieved. In medical institutions, new diagnostic methods and treatment options based on brain science research are beginning to be applied clinically, bringing new hope to patients. In rehabilitation institutions, personalized rehabilitation training programs have achieved promising results, with many patients experiencing significant improvements in limb function and language skills.

"I am extremely pleased to see our continuous progress in brain science research and application. I have a firm hope to expand the results for the benefit of mankind. In the future, we will continue to increase investment in research and development and expand the application areas. We plan to establish cooperative relationships with [X] medical institutions and [X] rehabilitation institutions in the next year to jointly promote the development and application of brain science. At the same time, we will strengthen cooperation with scientific research institutions, carry out cutting-edge research, and contribute more to conquering brain diseases." Mu Yang said proudly at an internal company meeting.

In the days to come, Mu Yang will continue to lead the biotechnology company and move forward firmly on the road of brain science research and application, allowing the deep integration of biotechnology culture and medical culture to create new glory for human health.