Doctor: I picked up attributes in the hospital

Chapter 184 Neural Stem Cell Transplantation

The next day.

Eight forty in the morning.

After the morning meeting, Gao Jun called Zhao Heng to the office.

"Xiao Zhao, Sun Xinxin will be sent here tonight, how are you preparing?"

Sitting on the sofa, Gao Jun asked Zhao Heng with great concern.

For the new Center of Anesthesia and Perioperative Medicine, receiving Sun Xinxin is now the top priority.

From the other side of the ocean to Beishi, due to some reasons, there is only a flight that arrives at [-]:[-] p.m., so Sun Xinxin's consultation will also be held at night.

"Every preparation is in place, and now it is waiting for someone to deliver it."

Zhao Heng said.

Speaking of which, although Sun Xinxin is a very important patient, the ICU is relatively complete with all kinds of equipment, so Zhao Heng completed the preparations without spending too much effort.

"This is all the medical records and information about Sun Xinxin from the Mayo Clinic. Please read it first."

Gao Jun opened the laptop on the coffee table, handed it to Zhao Heng and said.

"Ah."

Zhao Heng took the laptop from Gao Jun and began to look at it carefully.

After just watching for a while, Zhao Heng's expression became serious.

"Teacher, the situation is more serious than we estimated before. Judging from the information from Mayo, Sun Xinxin is now in a continuous vegetative state."

Zhao Heng said very solemnly.

With regard to the vegetative state, the clinical definition is: the body is periodically awake and asleep, but there is no evidence of cognition or behavior or brain metabolism expressed in response to external events or stimuli.

And when this cognitive loss persists for more than three months, it's called a persistent vegetative state.

In this state, the patient is completely a "living dead", not only completely lost the cognition of himself and the surrounding environment, but also lost the ability to understand and express language, fecal incontinence, sleep-wake cycle, hypothalamus and Brainstem autonomic function is fully or partially preserved.

"Yes, Sun Xinxin's situation, the Mayo Clinic has determined that it is a severe craniocerebral injury caused by axonal damage in the ascending reticular activation system of the brainstem. Sun Xinxin was treated at Mayo during his hospitalization. I did everything, but Sun Xinxin still didn't show any signs of waking up."

Gao Jun said very solemnly.

As the world's top hospital, the Mayo Clinic has cutting-edge treatment methods. After all these methods have been used, the patient still does not wake up. It can be said that, to a certain extent, Sun Xinxin was sentenced to death. "Death penalty".

"What do you think about Sun Xinxin's treatment?"

After a pause, Gao Jun asked again.

He looked forward to hearing different ideas from Zhao Heng.

In the past, Zhao Heng put forward ideas and solved problems several times when everyone was at a loss.

This is why Gao Jun valued Zhao Heng so much.

"I read the treatment records of the Mayo Clinic. Sun Xinxin has been given drugs to wake him up, as well as some music therapy and family therapy, but basically the effect is very small. Because Sun Xinxin still has a brainstem aneurysm in his brain. , Therefore, the means of electrical stimulation cannot be used.”

"So, I think that Sun Xinxin's brain cells have been severely damaged, and it may be difficult to wake her up with ordinary methods."

Zhao Heng said in an orderly manner.

"Xiao Zhao, what do you mean?"

Hearing what Zhao Heng said, Gao Jun couldn't wait to know if Zhao Heng had other ideas.

"I think some unconventional treatments for awakening can be tried, such as neural stem cell transplantation, gene therapy and embryonic brain tissue transplantation."

Zhao Heng expressed his thoughts. Since he learned from Gao Jun that Sun Xinxin was sent here, he has been thinking about what kind of treatment methods can be used for Sun Xinxin after she is sent here.

The treatments that the Mayo Clinic had already done had little effect, and there was clearly no need to repeat them.

"Gene therapy and embryonic brain tissue transplantation are still too far away from being practical, but this neural stem cell transplantation is a new idea."

When Gao Jun heard what Zhao Heng said, his eyes lit up and he said.

Neural stem cell transplantation is a method of transplanting neural stem cells into the host so that the neural stem cells can travel to and gather in the lesion of the nervous system, and survive, proliferate, and differentiate into neurons and glial cells, thereby promoting the partial recovery of the host's missing function. technology.

"Actually, there are many treatment methods for long-term coma at home and abroad, but so far, no specific treatment method has been found that can accelerate the recovery of patients' perception. There are various reasons for long-term coma, but for Sun Xinxin This patient, I think the biggest reason for his long-term coma, is most likely a severe traumatic brain injury, which damaged brain cells."

"So, through the means of neural stem cell transplantation, the damaged brain cells can be supplemented to the greatest extent, so that the brain function can be restored, so as to awaken the sleeping consciousness."

Zhao Heng said seriously.

Obviously, he was prepared, and the preparation was very detailed.

"Well, and neural stem cells can also be transplanted through arteriovenous injection. In this case, it can be said that there is no damage to the brain tissue, and it has no effect on the brainstem aneurysm in the patient. It is very worth a try."

Gao Jun nodded again and again. Obviously, Zhao Heng's idea was a great breakthrough for Sun Xinxin's treatment, which had stagnated at present.

Young people, just dare to think and dare to do it!
Thinking of this, Gao Jun couldn't help but glance at Zhao Heng with great satisfaction.

The best thing about the plan that Zhao Heng thought of was that there was no need to go to war, as long as the cerebrospinal fluid was extracted through spinal cord puncture, neural stem cells could be extracted from it, and then differentiated and cultivated, and then reinjected into the patient's body. up.

"The Mayo Clinic actually proposed the latest treatment plan, which is deep brain stimulation, which is a wake-up treatment that Mayo has been actively researching."

After a pause, Gao Jun said again.

"Sun Xinxin's family didn't agree?"

Zhao Heng asked with some doubts.

"Of course I disagree. According to our doctor there, Mayo internally believes that the success rate of deep brain stimulation is less than 30.00%, but it has to bear the risk of permanent damage to brain function due to brain stimulation. "

Gao Jun said slowly.

"This is really old beauty's thinking, simple and rude."

Zhao Heng said noncommittally.

To put it bluntly, deep brain stimulation for long-term comatose patients is the same mechanism as the use of electrical defibrillation for patients with cardiac arrest.

If the heart stops beating, I will give you a call, and if the brain is not active, I will also call you.

For patients with normal body functions and no serious brain damage, such a treatment may be tried.

But Sun Xinxin's situation is obviously different. Not only did she suffer from a very serious traumatic brain injury, but she also had an aneurysm in the brainstem. The effect of this "electricity" is unknown, but the complications and sequelae are serious.

This is the difference in the clinical thinking of doctors on both sides.

(End of this chapter)