Dressed as a big boss Bai Yueguang, God does not allow salted fish to lie down

The next day, Su Yuejian came to Renxin Hall and went straight to the research room at the back.

A glimmer of hope flashed in her eyes, and she couldn't wait to ask Shen Nanxing, "Is there any formula for a knockout drug? The kind used by the stunners?"

She felt that there might be some discovery here, and now she couldn't miss any possibility!

After more than ten days, hundreds of people searched together and found all the prescriptions for knockout drugs. Some doctors said it was henbane, some doctors said it was datura, and some folk remedies books said it was yam.

Baiji also found a recipe in unofficial historical biographies, Shengshuisan, which is composed of Datura, Aconitum powder, Scopolamine, Raw Arisaema, and Toad venom.

There are hundreds of prescriptions in the group of knockout drugs, but Datura is still a frequently used single drug.

Su Yuejian had a bold guess that the active ingredient of this Ma Fei San was very likely Datura.

Should this datura be made into powder before use, or should it be distilled and purified before use? Should the datura be boiled directly, or should it be distilled and stored together with alcohol?

Will other toxic substances be produced during the preparation process? Are there other adjuvants recorded in ancient prescriptions to enhance the anesthetic effect and reduce the toxic components at the same time?

Just when I had a clue, my head exploded again.

Su Yuejian shared her ideas with Shen Yuxin, Shen Nanxing and others.

Shen Yuxin saw that his little disciple was almost going insane, so he comforted him, "It's getting late, don't think about it for now. You are not alone here, we will find a solution together, you should go back and rest first.

We have a lot of people, and these commonly used medicinal prescriptions are not complicated for us to prepare. We can try the purification treatment, water treatment, heat treatment, vinegar treatment, and wine treatment one by one!"

Su Yuejian left Renxin Hall, sat in the carriage, closed her eyes and thought about the prescription.

In the distance, on the second floor of Lanyue Tower facing the street, Nangong Li was looking at a carriage with the Su Mansion emblem. The curtain of the carriage was blown by the wind. Nangong Li took a glance and saw a tired little face trying to think about something.

"What are you doing? Why are you so tired?"

Nangong Li felt a little sorry for the little person in the carriage, who was pushing himself so hard.

He thought that he would take her out to relax after she was done with her work. This little girl only had medical skills and making money in her eyes and mind, and she didn't have the slightest thought of a girl.

He smiled helplessly and dotingly, forget it, it's my fault for liking to be tortured.

Back in his own courtyard, Haoyuexuan, for more than a month, Su Yuejian went out before dawn every day and came back late at night. It felt like being in the hospital, and he was busy and exhausted.

Su Yuejian collapsed on the bed, not wanting to move at all.

She wanted to rest, why was she curling herself up like that, why couldn't she make herself more comfortable, why was she in such a hurry.

She was a little discouraged and wanted to give up and lie down.

If she does nothing, she won't cause trouble. If she doesn't cause trouble, no one will be implicated because of her. But if she doesn't solve the anesthesia problem, she will still not be able to perform surgery in the future!

Shaoyao and the other little maids in the yard saw this and felt very sorry for their master.

Shaoyao and Xiahe massaged her shoulders and neck; Qiuju and Dongmei were stronger, so they massaged her limbs; Chunlan prepared her favorite spicy hotpot; and Nanny Qin was sewing winter clothes for Su Yuejian.

They simply wanted to be nice to Su Yuejian, to care about her, and to help her relieve her fatigue.

Surrounded by such a loving atmosphere, Su Yuejian felt a little ashamed of her escapist behavior.

She wanted to try again, for herself and for these lovely people.

After working intensively for a month and a half, Su Yuejian now even dreams about the formula of anesthetics. Once, he even dreamed of a cloud of white mist. Su Yuejian asked him, "Who are you?"

Bai Wu said, "I am neither a human nor a fairy nor a demon nor a monster."

"What are you doing in my dream? Are you going to tell me the prescription for Ma Fei San?"

The white mist transformed into a human-like fog ball and said, "I do know the formula, but you have to research it yourself!"

"Are you the Heavenly Dao?"

"I am your Creator!"

Su Yuejian woke up in a sweat, she knew it was not just a dream, she had a hunch that this dream was related to the laws of heaven and earth, or perhaps to her coming to this inexplicable era.

At this moment, she felt another wave of vibration. This time, she tried hard to look for it and found that it was her skylark jade pendant that was vibrating. There was actually a line of small words flashing on it: [Alpha]. It flashed three times and then the information disappeared.

What does this mean? There is no beginning or end...

Su Yuejian sighed. This life was unbearable. This broken body, this weird creator, and how could this good jade pendant become like a pager? What was even more outrageous was the strange message on it [Alpha]...

What is all this?

If she can't figure it out, she can only put it aside for the time being. Maybe one day she will suddenly figure it out.

At least now we know that this jade pendant can transmit messages, but unfortunately it is only one-way.

There is no way to find out who the other party is.

Su Yuejian decided to carry the jade pendant with her at all times to prevent any information from being missed.

Su Yuejian woke up in the middle of the night, and couldn't fall asleep again with so many mysteries.

Now that you’re not sleepy anymore, let’s continue working hard!

So she began to review the progress of anesthesia again.

By studying a large number of prescriptions, she found that the herb "Datura" was included in many prescriptions.

It is recorded in "Biography of Hua Tuo" that "If the disease is internal and cannot be cured by acupuncture and medicine, the patient is first ordered to take Ma Fei San with wine. After he is drunk and unconscious, his abdomen and back are cut open to remove the accumulation." Ma Fei San is taken with wine.

Datura is an alkaloid herb, and its main medicinal effect is its toxic components: alkaloid drugs are used for their toxicity. If alkaloids are the active ingredients, their dissolution rate should be increased to minimize losses.

Ancient books record that Ma Fei San should be taken with wine, which should be used to increase the release of its effective ingredients.

After dawn, Su Yuejian washed up.

Nanny Qin thought to herself, others only know that the young lady is a miracle doctor, but they don’t know how hard she works.

Seeing that she had lost a lot of weight because of her research on anesthetics, Nanny Qin felt pain in her heart. She could only discipline the maids in the courtyard, take care of her food, clothing, housing and transportation, and prevent her from worrying about trivial matters. She could not help her with anything else.

As soon as the sun rose, Su Yuejian ran to Renxin Hall again and told it her guess.

At this time, Shen Nanxing said that they had processed the mandshurica in various ways, and found that the mandshurica had no effect after being boiled in water. After dozens of attempts, they found that this type of herbal medicine has the characteristics that auxiliary materials such as wine or vinegar should be selected to increase dissolution. For example, there are traditional Chinese medicines such as Corydalis yanhusuo cooked in vinegar and Coptis chinensis cooked in wine.

That’s right, it coincides with Su Yuejian’s guess.

The powder of Ma Fei San is a dry powder.

Based on this speculation, she would prepare the stems and leaves of Datura, obtain a dry powder, mix it with alcohol of different purity, and then purify the resulting liquid, which would be her experimental target, and then see which one would have better effect.

Su Yuejian asked Baiji to get three rabbits for the experiment and numbered them 3-1.

Dissolve raw datura powder in 50%/75%/100% alcohol purified solutions respectively, mark them as 50,75, 100, , and see which one has better reaction effect in the inhalation experiment later!

结果1号兔子迷晕了20分钟，2号兔子迷晕了30分钟，3号兔子迷晕了60分钟。

An hour later, all the rabbits were full of life and after a few days of observation, there were no sequelae.

This proves that this formula is almost non-toxic or weakly toxic to rabbits, and that the higher the alcohol concentration, the longer the anesthesia duration.

A few days later, the same three rabbits were used for open-chest surgery, this time using the liquid purified from raw datura with 100% pure alcohol. That is, the surgery was opened and turned over for more than half an hour, and then closed layer by layer to see if the depth of anesthesia was ideal.

It was found that the rabbits were sleeping soundly and unconscious during the operation, which showed that the anesthesia was very successful.

Su Yuejian was very happy with the result. She couldn't help but raise her head and smiled sweetly at everyone. The room was instantly filled with beauty!

Shen Nanxing, who was standing aside, stared at Su Yuejian infatuatedly, his eyes full of admiration and adoration!

At this moment, Su Yuejian is like a guiding star, giving people an irresistible attraction.

Shen Nanxing, on the other hand, is like a butterfly lost among flowers, at a loss but full of yearning.

The doctors at Renxin Hall seemed to have seen the emergence of anesthetics, and each of them was as excited as a child!

Don't worry, don't worry!

Now is not the time to be happy, there is still the most important hurdle to overcome!