godfather of surgery

Chapter 1212 Is that bottle really that pretty?

I almost missed the opportunity to be a pilot participant. I was just pleading for a Phase II clinical trial. The time difference between the two is huge, ranging from a few months to a year.

Adams was truly startled and didn't know how to describe his feelings; they were a mess. However, he was very happy that he could participate in the pilot experiment, which meant he could receive rapid treatment. He felt that it was probably his sincerity that made the difference, and that he had stood up to speak out for the truth.

Of course, his actions were commendable, eliminating the controversy surrounding him and making him eligible to be a volunteer. The absence of controversy is a prerequisite for becoming a volunteer, but this alone is not enough. There is another decisive factor in his case: bone tumors are relatively rare in the adult population, and the experiment needs patients of all ages, so his relatively rare case is what the experiment requires.

In fact, the so-called truth is not that important to Yang Ping, nor are the opposing opinions of those people. At worst, he can withdraw the clinical trials in Europe and America and carry out all the clinical trials in China. He will not suffer any losses at that time. He just needs to carry out his experiments step by step.

If we are forced to cancel the experiments in Europe and America, there will probably be a huge uproar there. The volunteers there are not like the volunteers here. The volunteers here are recruited according to standards, but the volunteers there are either important people themselves or their family members are important people. If these people cause trouble to cancel the experiments, it will be a matter of life and death for them.

"Is it true? Professor Yang, I had a misunderstanding. I beg you to let me participate in the Pioneer Experiment." Adams' happiness came so suddenly.

In fact, everyone's happiness is different at different times and in different circumstances. Adams now feels that the happiest thing is to be able to get treatment with the new therapy as soon as possible.

“Let him participate in the Pioneer Experiment. There is no controversy about his participation as a volunteer. He has already made his stance clear in the most powerful way,” Song Ziming said, speaking up for Adams.

Adams immediately seized the opportunity: "Yes, that's right, they don't represent me, and neither does my sister. Oh, I've cut ties with her. As an independent individual, I urgently request to join the volunteer program. I don't care about those hypocritical and stupid guys."

“Alright, let him stay and participate in the pioneer experiment.” Yang Ping agreed. Adams’ case was still very representative and of great experimental value. As long as he was willing, there would be no problem without any controversy.

"Oh, this is really exciting, Professor Yang. Tell me what I need to do now, and I'll cooperate with whatever you say." Adams spoke cautiously, his heart pounding, afraid that Professor Yang might change his mind.

Adams felt that this opportunity was like a giant soap bubble he was holding in his hands, which could burst at any moment. He had to hold his breath and do everything in his power to protect it and prevent it from breaking.

"You stay quietly in the ward and wait for our notification. Keep a good mood, get enough sleep, and do some moderate exercise to get your body into the best condition," Yang Ping instructed him.

Adams immediately wrote it down: "I will do it, please rest assured, Professor Yang, you are the greatest doctor in the world, you are like an angel descended to earth, you..."

The British also enjoy flattery; human nature is universal, and human weaknesses are similar, only sometimes manifested differently due to cultural differences.

Even Yang Ping himself felt embarrassed by the flattery, so he pretended not to hear it.

"Also, be careful not to catch a cold. If you get an acute upper respiratory infection or something similar, it will delay the experiment because it may affect the experimental data." Yang Ping quickly shut him up to stop him from continuing his British-style flattery.

"Don't worry, I will. I will definitely not let myself catch a cold." Now, Adams would pat his chest and guarantee anything.
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The following day, in the institute's ward, Sisi underwent a new course of treatment. This time, the K biological agent used was the latest model, which had undergone numerous improvements over the original. Scholars around the world were amazed at how quickly K therapy had evolved.

Sisi's spirits are improving, which is quite strange. Her cactus seems to have a spirit of its own, now turning lush and vibrant green. She lies quietly in her hospital bed, and the treatment seems very simple. The team is no longer as tense as before, and appears quite relaxed.

Sisi was prepared early in the morning. She lay in the hospital bed waiting for treatment. The nurse took her blood pressure and temperature and collected some basic vital signs. Everything was normal.

The K biological agent was delivered from the laboratory to the ward in a small portable refrigerator. The doctor and nurses checked and verified the biological agent to ensure it was in good condition before signing for receipt.

Sisi's parents also stayed by her bedside, waiting for the treatment to begin. Sisi's father was Yang Ping's driver, and her mother was a nursing assistant in the department, who usually assisted the nurses with some basic tasks, such as changing bed sheets and other daily care tasks.

The nurse came in to set up an intravenous line and hung up a bottle of saline solution. Sisi's parents tactfully left the ward. Doctors and nurses generally do not allow family members to be present when they are performing treatments, as this can easily interfere with the treatment.

"It's alright, you can stay in the ward and keep watch over her," the nurse told Sisi's parents.

But they know the rules. Even if the doctors and nurses agree, they can't break the rules. It's okay to wait outside; it's not like they're worried.

Yang Ping arrived at the ward, followed by more than a dozen doctors. In fact, this treatment was just like an IV drip, and there was nothing special about the procedure, but everyone still liked to follow along.

When the K biological agent was delivered, the nurse checked it and replaced the original saline solution with the K biological agent. It works like a regular intravenous drip and does not require any other special auxiliary medical equipment.

As the infusion line was reopened, the K biological agent was slowly infused into Sisi's blood vessels via intravenous infusion. It then circulated throughout her body via the bloodstream, and of course, it also entered the solid tumor lesion. Then, it penetrated the capillaries and entered the body fluids between cells, wandering in the intercellular spaces, searching for tumor cells, locking onto them, penetrating them, and hunting them down. The whole process was completely silent.

Thanks to excellent improvements, the K virus has become very weak in its fight against the human immune system, because it does not cause adverse damage to normal cells except for hunting tumor cells.

After receiving the K biological agent infusion, Sisi no longer needed to stay in her ward and was afraid to move around. She could walk around the hospital grounds and regularly complete various checkups to monitor the effectiveness of the treatment. Yang Ping studied all of Sisi's test results from her admission to the present. Since starting K therapy, her tumor lesions had been steadily decreasing. Although there had been some dramatic setbacks in the early stages of treatment, the overall direction was completely moving towards the goal of a cure.

During the research phase of this project, the system crashed, and Yang Ping completed the project without any system assistance. Of course, all the extensive knowledge he accumulated was acquired within the system.

"Professor, would you say this K virus is still considered an adenovirus? If you say it is an adenovirus, its function is completely related to viruses. If you say it's not an adenovirus, its main structure is still a protein shell enclosing nucleic acid. We just modified its original structure and installed some proteins with special functions on it," a PhD student next to him asked.

Everyone stood in the ward watching Sisi receive an IV drip. Actually, there wasn't much to see during the drip, but everyone was still gathered around, quite excited. Even the little girl was a bit embarrassed, as she had no side effects yet and still needed such a large team to "take care" of her.

"Hasn't the K virus already been renamed? It's called K protein complex. We're just used to calling it K virus. It's no longer a virus; it's a completely new type of artificially regenerated microorganism," Song Ziming replied, as Yang Ping was intently watching the upside-down K biological agent.

"It originated from the modification of adenovirus, but regardless of its structure or function, it has completely broken away from the category of virus. It is a completely new artificial species. Is a mule a horse or a donkey? It is neither. It is a completely new breed. The K protein complex is now more distant from adenovirus than a mule is from a horse," Song Ziming explained to them.

“Adenovirus is just a material we use. For example, we use a motor, rotor and frame to assemble a drone. Would you say the drone is still a frame?” Lu Xiaolu’s analogy is very good. It vividly illustrates the relationship between the K protein complex and adenovirus. In fact, adenovirus plays the role of a scaffold.

The research team installed many functional protein structures on this scaffold. Some of them have recognition functions, which can identify tumor cells, while others are responsible for penetration, enabling them to penetrate some substantial physical barriers, such as capillary walls, tumor septa, cell membranes, etc. This is why it can reach the interior of a solid tumor.

There are also some functional units, such as evading immune attacks and improving survival rate in the human body. Most importantly, it carries the K factor, which can initiate the apoptosis program inside tumor cells and kill them.

"In the future, we will use adenoviruses or other relatively harmless viruses as templates to create other therapeutic complex proteins. K therapy is not a single drug or biological agent; it will be a vast treatment system. I remember a famous scholar saying that cell therapy will become the largest medical specialty in the future, capable of curing the vast majority of diseases and eliminating many existing treatment methods. This is not an exaggeration, but a serious statement. I want to tell you all that our K therapy will be a more promising treatment system than parietal cell therapy. As you have seen, cell therapy has been stagnant in the treatment of solid tumors; it is only suitable for hematologic malignancies. Our K therapy, however, can theoretically treat both hematologic and solid tumors, as long as there is enough suitable K factor." Lu Xiaolu decided to give these guys another lesson. During his lectures, some of them always took it to heart.

"I believe Professor Lu's statement because the K protein complex is much smaller than a cell in volume, allowing it to perform various operations inside the cell. Therefore, the operational space for various cells must be much larger in the future," another PhD student said.

Sisi lay in bed receiving an IV drip, her eyes darting around as she looked at her older siblings surrounding her. What did they mean by this? Were they watching her get her IV drip, and then going to have a meeting and give a lecture? Well, even if she didn't understand, she'd listen along anyway.

"Viruses are far fewer than cells. Viruses are nanometers in diameter, while human cells are micrometers in diameter. The difference between the two is hundreds to thousands of times. Cells can be seen with an optical microscope, but viruses cannot be seen with an optical microscope at all. They can only be seen with an electron microscope." Sisi couldn't help but express her opinion.

"Hey! Senior sister, you're really right. How do you know so much? Do you have biology in elementary school? You'll learn this in middle school, right?" a PhD student teased Sisi.

Everyone calls Sisi "Senior Sister" now. Sisi looked quite serious and said, "I looked up information. I used the computer to look it up and also read some books. Anyway, that's all I know. Am I right?"

Song Ziming said, "That's right, that's how it is. It seems that Junior Sister really wants to be a doctor in the future."

Sisi said, "Of course, you all call me senior sister, how could this be fake? I'm determined to become a doctor in the future. Just you wait, I'm sure I can get into the eight-year program at Nandu Medical University."

"Oh, you even know about the eight-year system?" one of the graduate students seemed quite surprised.

Sisi said dismissively, "Many of you are in an eight-year program, how could I not know that? You seriously underestimate children's intelligence. I know you don't have a girlfriend?"

"How did you know?" the graduate student asked, blushing.

“I’ve run into you a few times at that milk tea shop next to the hospital, and you always buy one cup,” Sisi said.

She was right. This graduate student really didn't have a girlfriend. If he did have a girlfriend, or even a potential girlfriend, how could he only buy one cup of milk tea? He would have to bring one for his girlfriend too.

"You little rascal, you're so clever!" the graduate student said.

Suddenly, everyone fell silent because they realized that Professor Yang hadn't said a word yet. What was he doing? Song Ziming noticed that Yang Ping had been staring intently at the bottle of K biological agent, his gaze never leaving it.

Song Ziming didn't know what Yang Ping could glean from staring at the bottle, so he also stared at it, and then everyone stared at the bottle.

The head nurse felt uneasy under everyone's gaze; was there something wrong with the bottle?
She couldn't figure out what the problem was. If there was a problem, Professor Yang should have pointed it out, so why didn't he say anything?

Not only Professor Yang was staring at the bottle, but Xu Zhiliang was also staring at the bottle. Song Ziming didn't know why, but he also stared at the bottle. Everyone stopped chatting and stared at the bottle as well, but no one knew why they were staring at the bottle. They just followed along.

Is that bottle pretty? Even Sisi couldn't help but turn her head to look at it.